Mitch Hilligoss ripped an RBI triple and scored on Eduardo Nunez's single in the eighth for Charleston (11-8), which has won four straight. Nunez went 3-for-4 with a run-scoring triple in the third.
Catfish reliever Ryan Reid (4-4) took the loss after yielding two runs on three hits while striking out four in two innings. Starter Ryan Morse gave up a run on four hits and three walks with two strikeouts in five frames.
Nevin Ashley belted an RBI single in the seventh for Columbus (11-8).
The game was delayed over an hour because of rain. The 3-game series continues tonight.